There are a couple of similar definitions for this activity.

  1. This is the disturbing name for a game the involves mixing up pills (could be prescriptions, or any pills in a medicine cabinet) in a bowl to resemble the rainbow colored candy (Skittles) and then taking a random few.
  2. Called “skittling,” the term refers to young people substituting cough suppressants and a decongestant or antihistamine, often found in a little red pill, for the red candies found in a Skittles bag. Then the drugs are consumed by the handful.